Chronic Infections Episodes

What happens when all your supplements, clean eating, and protocols stop working—and you just keep getting sicker? Danielle Pashko had built her career in functional medicine, doing everything “right.” But after thyroid cancer, Lyme disease, and long COVID wrecked her health, she hit a wall. Nothing worked—until she stopped chasing fixes and started going inward. In this episode, Danielle shares how she finally started healing by rewiring her nervous system, using Qigong, martial arts, and visualization. She breaks down why most chronic illness approaches miss the mark, why emotions and stress regulation matter more than you think, and how she created a daily routine that actually stuck. If you’re stuck in a healing rut, frustrated with endless protocols, or just want to feel like yourself again—this one’s for yo

In this episode, Dr. Adam Rinde welcomes back microbiologist and PolyBio Research Foundation co-founder Dr. Amy Proal. Together, they unravel a framework for understanding chronic illnesses through the lens of persistent infections and their impact on mitochondria, immunity, and neurological health. Dr. Proal shares cutting-edge research linking pathogens like herpesviruses, cytomegalovirus, Epstein-Barr, and even latent parasites to conditions like Alzheimer’s, long COVID, chronic fatigue syndrome, POTS, and more. Discover how stealth microbes can disrupt the vagus nerve, hijack mitochondrial energy systems, and weaken immune responses, setting the stage for a cascade of chronic dysfunctions. The conversation dives deep into the role of immune modulation, including promising findings around low-dose rapamycin and its potential to restore immune signaling and combat viral persistence. They also explore diet, metabolic interventions, and new clinical trials shaping the future of …

What happens when you blend ancient wisdom with the frontiers of modern medicine? Prepare to have your perspective expanded in this captivating episode of The One Thing Podcast, featuring Gillian Ehrlich, DNP, ARNP. Join Dr. Adam Rinde as he explores Gillian's remarkable journey, from a childhood shaped by environmental awareness to her pioneering work in integrative healthcare. Discover how she seamlessly weaves #Ayurveda – a healing tradition stretching back millennia – with contemporary therapies like #plasmapheresis and #ketamine-assisted psychotherapy. This isn't just about treatments; it's about a philosophy. Gillian shares her profound belief in honoring each individual's unique path to wellness, moving beyond the pursuit of "normal" to celebrate the power of being truly yourself. She illuminates how understanding individual patterns and #doshas can unlock deeper healing potential, and discusses the challenges (and triumphs) of integrating this holistic approach into a s…

In this episode of The One Thing Podcast, hosted by Dr. Adam Rinde, the focus is on integrative and naturopathic medicine, specifically addressing complex chronic illnesses and cancer care. Dr. Rinde introduces the guest, Dr. Paul Anderson, a leading voice in the field with over 30 years of clinical experience. The episode aims to explore the topic of coagulopathy in chronic disease, discussing its mechanisms, implications, and potential treatments.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition with symptoms of persistent fatigue, neuroinflammation, post-exertional fatigue, joint pain, nerve pain, muscle pain, sensory hypersensitivity, disturbed sleep, headaches, and bowel changes. It often takes years to get a proper diagnosis and most patients are brushed off as having a psychosomatic illness. ' Thanks to researchers like our guest Dr. Amy Proal; we know so much more ME/CFS. It turns out there c...

Biofilm are communities of bacteria that form in many places in the body including the lumen of the gut where bacteria transition from a free forming and moving organism into joining a community of bacteria living in a unit called biofilm. Biofilms are most acknowledged in dentistry as the purpose of flossing is largely to disrupt biofilm. Also, they are of grave concern in medicine as biofilms often form to the detriment of the host on implants, tubes, and catheters. The significance of biofi...

What is driving Autoimmunity? Is it time to turn our beliefs about autoimmune conditions around and look at what is the underlying cause? According many researchers, including our guest Dr. Amy Proal , a key driver of autoimmunity might be microbe based. As researchers are finding out specific microbes that turn pathogenic called "pathobionts" may be leading to a chronic inflammatory process that goes unchecked. In this episode we dive into pathobionts, intestinal permeability, the problem with ...

Autophagy is a term that refers to cellular self-digestion. We have heard the term self-attack-self in situations like autoimmunity; Well this a different type of process that is a normal every day process in the cell of cellular self-digestion. Technically autophagy is a catabolic metabolic program/process that is activated when intracellular nutrient uptake or availability is diminished. It was coined in the 1960’s by the late Christian de Nuve. It has resurfaced quite predominately since Yosh...